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By analyzing the FRET efficiency with FRET reporters placed at the C-termini of full-length GHR and C-terminal truncations, it was found, in general, that the dimeric-GHR ICDs are positioned at a greater distance apart, the further they are from the transmembrane domain (50)

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Discussion PTMs is a biological process in which small-molecule substrate, such as acetyl-CoA, crotonyl-CoA, butyryl-CoA, phosphate, etc, is covalently bound to a specific amino acid residue of proteins in a reversible manner