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Interactions with Benzodiazepines and Other CNS Depressants Inform patients and caregivers that potentially fatal additive effects may occur if hydrocodone bitartrate and acetaminophen tablets are used with benzodiazepines and other CNS depressants, including alcohol (e.g., non-benzodiazepines, sedative/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, gabapentinoids [gabapentin or pregabalin], and other opioids), and not to use these concomitantly unless supervised by a healthcare provider (see WARNINGS and PRECAUTIONS, Drug Interactions)

Sizar O, Leslie S, Schwartz J

Be realistic: Benefits in humans are not proven and research is ongoing

Every order includes batch-specific analytical documentation a Certificate of Analysis covering purity and identity