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Furthermore, mtROS can oxidize tetrahydrobiopterin (BH4), causing endothelial Nitric Oxide Synthase (eNOS) uncouplingwhere eNOS produces superoxide anions instead of NOfurther increasing oxidative stress and reducing NO bioavailability (Wang G

At the present time in the USA, BO is defined as an extension of salmon-coloured mucosa into the distal oesophagus 1 cm above the gastro-oesophageal junction (GOJ) with histological confirmation of SIM

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Genet Mol Res 10(1):419428 Siju S, Dhanya K, Syamkumar S, Sasikumar B, Sheeja TE, Bhat AI, Parthasarathy VA (2010a) Development, characterization and cross species amplification of polymorphic microsatellite markers from expressed sequence tags of turmeric ( Curcuma longa L.)