For the male partner, this would include 1,2 : Previous fertility and other reproductive issues Sexual activity, libido, and function Past and present medical conditions and medication usage Childhood conditions affecting the reproductive system, such as undescended testicle(s), mumps orchitis, and early puberty Physical or surgical trauma affecting the reproductive tract Alcohol, cigarette, and recreational drug use Occupation and other potential sources of environmental toxin exposure Family history of infertility or other medical conditions Physical examination A screening physical exam can be helpful in identifying lesions, cysts, tumors, varicoceles, and structural abnormalities related to the penis, vas deferens, epididymis, and testicles that may require further assessment
Ascoli 60
Notably, the paper reported a clear doseresponse relationship, further suggesting a pharmacological effect of GLP-1RAs on inflammatory pathways in PsO including metabolic benefits (59)
It also plays an important role in maintaining proper immune function